Comparative characterization of hexose transporters of Plasmodium knowlesi, Plasmodium yoelii and Toxoplasma gondii highlights functional differences within the apicomplexan family.

Chemotherapy of apicomplexan parasites is limited by emerging drug resistance or lack of novel targets. PfHT1, the Plasmodium falciparum hexose transporter 1, is a promising new drug target because asexual-stage malarial parasites depend wholly on glucose for energy. We have performed a comparative...

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Detalhes bibliográficos
Main Authors: Joët, Thierry, Holterman, Lennart, Stedman, Timothy T, Kocken, Clemens H M, Van Der Wel, Annemarie, Thomas, Alan W, Krishna, Sanjeev
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223042/
https://ncbi.nlm.nih.gov/pubmed/12238947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021189
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