Comparative characterization of hexose transporters of Plasmodium knowlesi, Plasmodium yoelii and Toxoplasma gondii highlights functional differences within the apicomplexan family.

Chemotherapy of apicomplexan parasites is limited by emerging drug resistance or lack of novel targets. PfHT1, the Plasmodium falciparum hexose transporter 1, is a promising new drug target because asexual-stage malarial parasites depend wholly on glucose for energy. We have performed a comparative...

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Détails bibliographiques
Auteurs principaux: Joët, Thierry, Holterman, Lennart, Stedman, Timothy T, Kocken, Clemens H M, Van Der Wel, Annemarie, Thomas, Alan W, Krishna, Sanjeev
Format: Artigo
Langue:Inglês
Publié: 2002
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223042/
https://ncbi.nlm.nih.gov/pubmed/12238947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021189
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