Role of Gamma Interferon and Interleukin-4 in Host Defense against the Human Filarial Parasite Brugia malayi

We have investigated the roles of gamma interferon (IFN-γ) and interleukin-4 (IL-4) in host defense against Brugia malayi. Our data suggest that the lack of either IFN-γ or IL-4 prolongs the time required to achieve sterile immunity, suggesting that both canonical type 1 and type 2 responses are inv...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Babu, Subash, Ganley, Lisa M., Klei, Thomas R., Shultz, Leonard D., Rajan, T. V.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Fungal and Parasitic Infections
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97525/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10769010/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.5.3034-3035.2000
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