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Mice Genetically Deficient in Immunoglobulin E Are More Permissive Hosts than Wild-Type Mice to a Primary, but Not Secondary, Infection with the Filarial Nematode Brugia malayi

Primary and secondary murine and human infections with Brugia malayi are characterized by substantial increases in levels of immunoglobulin E (IgE). To investigate whether this is necessary for worm clearance, IgE(−/−) mice were subjected to primary- and secondary-infection protocols. Following a pr...

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Detalhes bibliográficos
Main Authors: Spencer, L. A., Porte, P., Zetoff, C., Rajan, T. V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153289/
https://ncbi.nlm.nih.gov/pubmed/12704117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.5.2462-2467.2003
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