Heme acquisition in the parasitic filarial nematode Brugia malayi

Nematodes lack a heme biosynthetic pathway and must acquire heme from exogenous sources. Given the indispensable role of heme, this auxotrophy may be exploited to develop drugs that interfere with heme uptake in parasites. Although multiple heme-responsive genes (HRGs) have been characterized within...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:FASEB J
Prif Awduron: Luck, Ashley N., Yuan, Xiaojing, Voronin, Denis, Slatko, Barton E., Hamza, Iqbal, Foster, Jeremy M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Federation of American Societies for Experimental Biology 2016
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024691/
https://ncbi.nlm.nih.gov/pubmed/27363426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600603R
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