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Heme acquisition in the parasitic filarial nematode Brugia malayi
Nematodes lack a heme biosynthetic pathway and must acquire heme from exogenous sources. Given the indispensable role of heme, this auxotrophy may be exploited to develop drugs that interfere with heme uptake in parasites. Although multiple heme-responsive genes (HRGs) have been characterized within...
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| Pubblicato in: | FASEB J |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Federation of American Societies for Experimental Biology
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5024691/ https://ncbi.nlm.nih.gov/pubmed/27363426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600603R |
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