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Heme acquisition in the parasitic filarial nematode Brugia malayi

Nematodes lack a heme biosynthetic pathway and must acquire heme from exogenous sources. Given the indispensable role of heme, this auxotrophy may be exploited to develop drugs that interfere with heme uptake in parasites. Although multiple heme-responsive genes (HRGs) have been characterized within...

詳細記述

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書誌詳細
出版年:FASEB J
主要な著者: Luck, Ashley N., Yuan, Xiaojing, Voronin, Denis, Slatko, Barton E., Hamza, Iqbal, Foster, Jeremy M.
フォーマット: Artigo
言語:Inglês
出版事項: Federation of American Societies for Experimental Biology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024691/
https://ncbi.nlm.nih.gov/pubmed/27363426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600603R
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