Toll-Like Receptor 4-Deficient Mice Have Reduced Bone Destruction following Mixed Anaerobic Infection

C3H/HeJ mice have an impaired ability to respond to lipopolysaccharide (LPS) due to a mutation in the gene that encodes Toll-like receptor 4 (TLR4). The effect of TLR4 deficiency on host responses to endodontic infections is unknown. In the present study, we compared periapical bone destruction, sep...

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Bibliographic Details
Main Authors: Hou, Linda, Sasaki, Hajime, Stashenko, Philip
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC98410/
https://ncbi.nlm.nih.gov/pubmed/10899873
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