Toll-Like Receptor 2 Deficiency Delays Pneumococcal Phagocytosis and Impairs Oxidative Killing by Granulocytes

Phagocytosis and killing of Streptococcus pneumoniae was compared in blood-derived wild-type (WT) and Toll-like receptor 2 (TLR2)-deficient (TLR2(−/−)) polymorphonuclear leukocytes (PMN). Phagocytosis of green fluorescent protein-transformed pneumococci was delayed in TLR2(−/−) PMN. These cells exhi...

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Bibliografiske detaljer
Main Authors: Letiembre, Maryse, Echchannaoui, Hakim, Bachmann, Philipp, Ferracin, Fabrizia, Nieto, Concepción, Espinosa, Manuel, Landmann, Regine
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307087/
https://ncbi.nlm.nih.gov/pubmed/16299338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.12.8397-8401.2005
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