Evaluation of Phase Variation of Nontypeable Haemophilus influenzae Lipooligosaccharide during Nasopharyngeal Colonization and Development of Otitis Media in the Chinchilla Model

Nontypeable Haemophilus influenzae (NTHI) has four loci, lic-1 to lic-3 and lgtC, that generate phase-variable lipooligosaccharide (LOS) structures. lic-1, which is required for the expression of phosphorylcholine (ChoP), is the best characterized and is associated with an enhanced ability of H. inf...

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Bibliographic Details
Main Authors: Tong, H. H., Blue, L. E., James, M. A., Chen, Y. P., DeMaria, T. F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Bacterial Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC98384/
https://ncbi.nlm.nih.gov/pubmed/10899860
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