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Evaluation of Phase Variation of Nontypeable Haemophilus influenzae Lipooligosaccharide during Nasopharyngeal Colonization and Development of Otitis Media in the Chinchilla Model

Nontypeable Haemophilus influenzae (NTHI) has four loci, lic-1 to lic-3 and lgtC, that generate phase-variable lipooligosaccharide (LOS) structures. lic-1, which is required for the expression of phosphorylcholine (ChoP), is the best characterized and is associated with an enhanced ability of H. inf...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Tong, H. H., Blue, L. E., James, M. A., Chen, Y. P., DeMaria, T. F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98384/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10899860/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.8.4593-4597.2000
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