Evaluation of Phase Variation of Nontypeable Haemophilus influenzae Lipooligosaccharide during Nasopharyngeal Colonization and Development of Otitis Media in the Chinchilla Model

Nontypeable Haemophilus influenzae (NTHI) has four loci, lic-1 to lic-3 and lgtC, that generate phase-variable lipooligosaccharide (LOS) structures. lic-1, which is required for the expression of phosphorylcholine (ChoP), is the best characterized and is associated with an enhanced ability of H. inf...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Tong, H. H., Blue, L. E., James, M. A., Chen, Y. P., DeMaria, T. F.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Bacterial Infections
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98384/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10899860/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.8.4593-4597.2000
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