The C Terminus of Component C2II of Clostridium botulinum C2 Toxin Is Essential for Receptor Binding

The binary Clostridium botulinum C2 toxin consists of two separate proteins, the binding component C2II (80.5 kDa) and the actin-ADP-ribosylating enzyme component C2I (49.4 kDa). For its cytotoxic action, C2II binds to a cell membrane receptor and induces cell entry of C2I via receptor-mediated endo...

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Xehetasun bibliografikoak

Argitaratua izan da:	Infect Immun
Egile Nagusiak:	Blöcker, Dagmar, Barth, Holger, Maier, Elke, Benz, Roland, Barbieri, Joseph T., Aktories, Klaus
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 2000
Gaiak:	Molecular and Cellular Pathogenesis
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98375/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10899856/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.8.4566-4573.2000
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