Passive Immunization with Melanin-Binding Monoclonal Antibodies Prolongs Survival of Mice with Lethal Cryptococcus neoformans Infection

Passive immunization with monoclonal antibodies (MAbs) to melanin prolonged the survival of and reduced the fungal burden in Cryptococcus neoformans-infected mice in comparison to controls. MAbs to melanin reduced the growth rate of in vitro-melanized C. neoformans cells, suggesting a new mechanism...

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Bibliographische Detailangaben
Hauptverfasser: Rosas, Ángel L., Nosanchuk, Joshua D., Casadevall, Arturo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98300/
https://ncbi.nlm.nih.gov/pubmed/11292764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.3410-3412.2001
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