Passive Immunization with Melanin-Binding Monoclonal Antibodies Prolongs Survival of Mice with Lethal Cryptococcus neoformans Infection

Passive immunization with monoclonal antibodies (MAbs) to melanin prolonged the survival of and reduced the fungal burden in Cryptococcus neoformans-infected mice in comparison to controls. MAbs to melanin reduced the growth rate of in vitro-melanized C. neoformans cells, suggesting a new mechanism...

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Detalhes bibliográficos
Main Authors: Rosas, Ángel L., Nosanchuk, Joshua D., Casadevall, Arturo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98300/
https://ncbi.nlm.nih.gov/pubmed/11292764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.3410-3412.2001
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