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Passive Immunization with Melanin-Binding Monoclonal Antibodies Prolongs Survival of Mice with Lethal Cryptococcus neoformans Infection

Passive immunization with monoclonal antibodies (MAbs) to melanin prolonged the survival of and reduced the fungal burden in Cryptococcus neoformans-infected mice in comparison to controls. MAbs to melanin reduced the growth rate of in vitro-melanized C. neoformans cells, suggesting a new mechanism...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Rosas, Ángel L., Nosanchuk, Joshua D., Casadevall, Arturo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2001
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98300/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11292764/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.5.3410-3412.2001
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