Antibodies to a Surface-Exposed, N-terminal Domain of Aggregation Substance Are Not Protective in the Rabbit Model of Enterococcus faecalis Infective Endocarditis

The aggregation substance (AS) surface protein from Enterococcus faecalis has been implicated as an important virulence factor for the development of infective endocarditis. To evaluate the role of antibodies specific for Asc10 (the AS protein from the conjugative plasmid pCF10) in protective immuni...

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Detalhes bibliográficos
Main Authors: McCormick, John K., Hirt, Helmut, Waters, Christopher M., Tripp, Timothy J., Dunny, Gary M., Schlievert, Patrick M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98289/
https://ncbi.nlm.nih.gov/pubmed/11292753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.3305-3314.2001
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