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Antibodies to a Surface-Exposed, N-terminal Domain of Aggregation Substance Are Not Protective in the Rabbit Model of Enterococcus faecalis Infective Endocarditis

The aggregation substance (AS) surface protein from Enterococcus faecalis has been implicated as an important virulence factor for the development of infective endocarditis. To evaluate the role of antibodies specific for Asc10 (the AS protein from the conjugative plasmid pCF10) in protective immuni...

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Bibliografiske detaljer
Main Authors: McCormick, John K., Hirt, Helmut, Waters, Christopher M., Tripp, Timothy J., Dunny, Gary M., Schlievert, Patrick M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98289/
https://ncbi.nlm.nih.gov/pubmed/11292753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.3305-3314.2001
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