Antibodies to a Surface-Exposed, N-terminal Domain of Aggregation Substance Are Not Protective in the Rabbit Model of Enterococcus faecalis Infective Endocarditis

The aggregation substance (AS) surface protein from Enterococcus faecalis has been implicated as an important virulence factor for the development of infective endocarditis. To evaluate the role of antibodies specific for Asc10 (the AS protein from the conjugative plasmid pCF10) in protective immuni...

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Autores principales: McCormick, John K., Hirt, Helmut, Waters, Christopher M., Tripp, Timothy J., Dunny, Gary M., Schlievert, Patrick M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Microbial Immunity and Vaccines
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC98289/
https://ncbi.nlm.nih.gov/pubmed/11292753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.3305-3314.2001
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