Antimycobacterial Agent Based on mRNA Encoding Human β-Defensin 2 Enables Primary Macrophages To Restrict Growth of Mycobacterium tuberculosis

Human macrophages are hosts for Mycobacterium tuberculosis, the causative agent of tuberculosis, which killed approximately 1.87 million people in 1997. Human alveolar macrophages do not express α- or β-defensins, broad-spectrum antimicrobial peptides which are expressed in macrophages from other sp...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Kisich, Kevin O., Heifets, Leonid, Higgins, Michael, Diamond, Gill
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Host Response and Inflammation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98208/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11254636/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.4.2692-2699.2001
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