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Antimycobacterial Agent Based on mRNA Encoding Human β-Defensin 2 Enables Primary Macrophages To Restrict Growth of Mycobacterium tuberculosis

Human macrophages are hosts for Mycobacterium tuberculosis, the causative agent of tuberculosis, which killed approximately 1.87 million people in 1997. Human alveolar macrophages do not express α- or β-defensins, broad-spectrum antimicrobial peptides which are expressed in macrophages from other sp...

詳細記述

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書誌詳細
主要な著者: Kisich, Kevin O., Heifets, Leonid, Higgins, Michael, Diamond, Gill
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC98208/
https://ncbi.nlm.nih.gov/pubmed/11254636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.4.2692-2699.2001
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