Antimycobacterial Agent Based on mRNA Encoding Human β-Defensin 2 Enables Primary Macrophages To Restrict Growth of Mycobacterium tuberculosis

Human macrophages are hosts for Mycobacterium tuberculosis, the causative agent of tuberculosis, which killed approximately 1.87 million people in 1997. Human alveolar macrophages do not express α- or β-defensins, broad-spectrum antimicrobial peptides which are expressed in macrophages from other sp...

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Bibliografiska uppgifter
Huvudupphovsmän: Kisich, Kevin O., Heifets, Leonid, Higgins, Michael, Diamond, Gill
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2001
Ämnen:
Host Response and Inflammation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC98208/
https://ncbi.nlm.nih.gov/pubmed/11254636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.4.2692-2699.2001
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