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Antimycobacterial Agent Based on mRNA Encoding Human β-Defensin 2 Enables Primary Macrophages To Restrict Growth of Mycobacterium tuberculosis

Human macrophages are hosts for Mycobacterium tuberculosis, the causative agent of tuberculosis, which killed approximately 1.87 million people in 1997. Human alveolar macrophages do not express α- or β-defensins, broad-spectrum antimicrobial peptides which are expressed in macrophages from other sp...

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Kisich, Kevin O., Heifets, Leonid, Higgins, Michael, Diamond, Gill
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2001
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98208/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11254636/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.4.2692-2699.2001
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