Tumor Necrosis Factor Alpha Increases Human Cerebral Endothelial Cell Gb(3) and Sensitivity to Shiga Toxin

Hemolytic uremic syndrome (HUS) is associated with intestinal infection by enterohemorrhagic Escherichia coli strains that produce Shiga toxins. Globotriaosylceramide (Gb(3)) is the functional receptor for Shiga toxin, and tumor necrosis factor alpha (TNF-α) upregulates Gb(3) in both human macrovasc...

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Bibliografiset tiedot
Päätekijät: Eisenhauer, Patricia B., Chaturvedi, Prasoon, Fine, Richard E., Ritchie, Andrew J., Pober, Jordan S., Cleary, Thomas G., Newburg, David S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2001
Aiheet:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC98098/
https://ncbi.nlm.nih.gov/pubmed/11179369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.3.1889-1894.2001
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