Tumor Necrosis Factor Alpha Increases Human Cerebral Endothelial Cell Gb(3) and Sensitivity to Shiga Toxin

Hemolytic uremic syndrome (HUS) is associated with intestinal infection by enterohemorrhagic Escherichia coli strains that produce Shiga toxins. Globotriaosylceramide (Gb(3)) is the functional receptor for Shiga toxin, and tumor necrosis factor alpha (TNF-α) upregulates Gb(3) in both human macrovasc...

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Dades bibliogràfiques

Publicat a:	Infect Immun
Autors principals:	Eisenhauer, Patricia B., Chaturvedi, Prasoon, Fine, Richard E., Ritchie, Andrew J., Pober, Jordan S., Cleary, Thomas G., Newburg, David S.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2001
Matèries:	Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98098/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11179369/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.3.1889-1894.2001
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