DsrA-Deficient Mutant of Haemophilus ducreyi Is Impaired in Its Ability To Infect Human Volunteers

Haemophilus ducreyi produces an outer membrane protein called DsrA, which is required for serum resistance. An isogenic dsrA mutant, FX517, was constructed previously in H. ducreyi 35000. Compared to its parent, FX517 cannot survive in normal human serum. When complemented in trans with a plasmid co...

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Bibliographische Detailangaben
Hauptverfasser: Bong, Cliffton T. H., Throm, Robert E., Fortney, Kate R., Katz, Barry P., Hood, Antoinette F., Elkins, Christopher, Spinola, Stanley M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Molecular Pathogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98046/
https://ncbi.nlm.nih.gov/pubmed/11179317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.3.1488-1491.2001
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