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DsrA-Deficient Mutant of Haemophilus ducreyi Is Impaired in Its Ability To Infect Human Volunteers

Haemophilus ducreyi produces an outer membrane protein called DsrA, which is required for serum resistance. An isogenic dsrA mutant, FX517, was constructed previously in H. ducreyi 35000. Compared to its parent, FX517 cannot survive in normal human serum. When complemented in trans with a plasmid co...

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Detalhes bibliográficos
Main Authors: Bong, Cliffton T. H., Throm, Robert E., Fortney, Kate R., Katz, Barry P., Hood, Antoinette F., Elkins, Christopher, Spinola, Stanley M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98046/
https://ncbi.nlm.nih.gov/pubmed/11179317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.3.1488-1491.2001
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