Expression of Cytolethal Distending Toxin and Hemolysin Is Not Required for Pustule Formation by Haemophilus ducreyi in Human Volunteers

Haemophilus ducreyi makes cytolethal distending toxin (CDT) and hemolysin. In a previous human challenge trial, an isogenic hemolysin-deficient mutant caused pustules with a rate similar to that of its parent. To test whether CDT was required for pustule formation, six human subjects were inoculated...

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Detalhes bibliográficos
Main Authors: Young, Royden S., Fortney, Kate R., Gelfanova, Valentina, Phillips, Carrie L., Katz, Barry P., Hood, Antoinette F., Latimer, Jo L., Munson, Robert S., Hansen, Eric J., Spinola, Stanley M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98108/
https://ncbi.nlm.nih.gov/pubmed/11179379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.3.1938-1942.2001
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