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Human Lactoferrin and Peptides Derived from Its N Terminus Are Highly Effective against Infections with Antibiotic-Resistant Bacteria

Since human lactoferrin (hLF) binds to bacterial products through its highly positively charged N terminus, we investigated which of the two cationic domains is involved in its bactericidal activity. The results revealed that hLF lacking the first three residues (hLF(−3N)) was less efficient than hL...

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Publicat a:Infect Immun
Autors principals: Nibbering, P. H., Ravensbergen, E., Welling, M. M., van Berkel, L. A., van Berkel, P. H. C., Pauwels, E. K. J., Nuijens, J. H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2001
Matèries:
Bacterial Infections
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98043/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11179314/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.3.1469-1476.2001
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