Internal Thiols and Reactive Oxygen Species in Candidacidal Activity Exerted by an N-Terminal Peptide of Human Lactoferrin

We previously showed that the energized mitochondrion and extracellular ATP are essential for the candidacidal activity of the N-terminal peptide of human lactoferrin, subsequently referred to as hLF(1-11). The present study focuses on the involvement of internal thiols and reactive oxygen species (...

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Detalhes bibliográficos
Main Authors: Lupetti, Antonella, Paulusma-Annema, Akke, Senesi, Sonia, Campa, Mario, van Dissel, Jaap T., Nibbering, Peter H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127236/
https://ncbi.nlm.nih.gov/pubmed/12019068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.6.1634-1639.2002
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