Human Lactoferrin and Peptides Derived from Its N Terminus Are Highly Effective against Infections with Antibiotic-Resistant Bacteria

Since human lactoferrin (hLF) binds to bacterial products through its highly positively charged N terminus, we investigated which of the two cationic domains is involved in its bactericidal activity. The results revealed that hLF lacking the first three residues (hLF(−3N)) was less efficient than hL...

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Podrobná bibliografie

Vydáno v:	Infect Immun
Hlavní autoři:	Nibbering, P. H., Ravensbergen, E., Welling, M. M., van Berkel, L. A., van Berkel, P. H. C., Pauwels, E. K. J., Nuijens, J. H.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2001
Témata:	Bacterial Infections
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98043/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11179314/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.3.1469-1476.2001
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