Macrophage-Derived Cell Lines Do Not Express Proinflammatory Cytokines after Exposure to Bacillus anthracis Lethal Toxin

We present evidence that Bacillus anthracis lethal toxin (LT) suppresses rather than induces proinflammatory cytokine production in macrophages. Suppression is observed with extremely low levels of LT and involves inhibition of transcription of cytokine messenger RNA. Thus, LT may contribute to anth...

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Detaylı Bibliyografya
Asıl Yazarlar: Erwin, James L., DaSilva, Luis M., Bavari, Sina, Little, Stephen F., Friedlander, Arthur M., Chanh, Tran C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2001
Konular:
Host Response and Inflammation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC98000/
https://ncbi.nlm.nih.gov/pubmed/11160016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.2.1175-1177.2001
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