Macrophage-Derived Cell Lines Do Not Express Proinflammatory Cytokines after Exposure to Bacillus anthracis Lethal Toxin

We present evidence that Bacillus anthracis lethal toxin (LT) suppresses rather than induces proinflammatory cytokine production in macrophages. Suppression is observed with extremely low levels of LT and involves inhibition of transcription of cytokine messenger RNA. Thus, LT may contribute to anth...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Erwin, James L., DaSilva, Luis M., Bavari, Sina, Little, Stephen F., Friedlander, Arthur M., Chanh, Tran C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2001
Pynciau:
Host Response and Inflammation
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC98000/
https://ncbi.nlm.nih.gov/pubmed/11160016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.2.1175-1177.2001
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