Macrophage-Derived Cell Lines Do Not Express Proinflammatory Cytokines after Exposure to Bacillus anthracis Lethal Toxin

We present evidence that Bacillus anthracis lethal toxin (LT) suppresses rather than induces proinflammatory cytokine production in macrophages. Suppression is observed with extremely low levels of LT and involves inhibition of transcription of cytokine messenger RNA. Thus, LT may contribute to anth...

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Autors principals: Erwin, James L., DaSilva, Luis M., Bavari, Sina, Little, Stephen F., Friedlander, Arthur M., Chanh, Tran C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Host Response and Inflammation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC98000/
https://ncbi.nlm.nih.gov/pubmed/11160016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.2.1175-1177.2001
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