Bacillus anthracis lethal toxin induces TNF-α–independent hypoxia-mediated toxicity in mice

Bacillus anthracis lethal toxin (LT) is the major virulence factor of anthrax and reproduces most of the laboratory manifestations of the disease in animals. We studied LT toxicity in BALB/cJ and C57BL/6J mice. BALB/cJ mice became terminally ill earlier and with higher frequency than C57BL/6J mice....

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Main Authors: Moayeri, Mahtab, Haines, Diana, Young, Howard A., Leppla, Stephen H.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2003
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC182199/
https://ncbi.nlm.nih.gov/pubmed/12952916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317991
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