Bacillus anthracis lethal toxin induces TNF-α–independent hypoxia-mediated toxicity in mice

Bacillus anthracis lethal toxin (LT) is the major virulence factor of anthrax and reproduces most of the laboratory manifestations of the disease in animals. We studied LT toxicity in BALB/cJ and C57BL/6J mice. BALB/cJ mice became terminally ill earlier and with higher frequency than C57BL/6J mice....

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Moayeri, Mahtab, Haines, Diana, Young, Howard A., Leppla, Stephen H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2003
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182199/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12952916/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17991
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