Identification and Characterization of a Novel Family of Pneumococcal Proteins That Are Protective against Sepsis

Four pneumococcal genes (phtA, phtB, phtD, and phtE) encoding a novel family of homologous proteins (32 to 87% identity) were identified from the Streptococcus pneumoniae genomic sequence. These open reading frames were selected as potential vaccine candidates based upon their possession of hydropho...

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Main Authors: Adamou, John E., Heinrichs, Jon H., Erwin, Alice L., Walsh, William, Gayle, Tony, Dormitzer, Melissa, Dagan, Ron, Brewah, Yambasu A., Barren, Philip, Lathigra, Raju, Langermann, Solomon, Koenig, Scott, Johnson, Syd
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC97974/
https://ncbi.nlm.nih.gov/pubmed/11159990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.2.949-958.2001
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