Pneumococcal Surface Protein A Is Expressed In Vivo, and Antibodies to PspA Are Effective for Therapy in a Murine Model of Pneumococcal Sepsis

Pneumococcal surface protein A (PspA) is an immunogenic protein expressed on the surface of all strains of Streptococcus pneumoniae (pneumococcus) and induces antibodies which protect against invasive infection in mice. Pneumococci used for infectious challenge in protection studies are typically co...

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Detalhes bibliográficos
Main Authors: Swiatlo, E., King, J., Nabors, G. S., Mathews, B., Briles, D. E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC308907/
https://ncbi.nlm.nih.gov/pubmed/14638806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.12.7149-7153.2003
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