Pneumococcal Surface Protein A Is Expressed In Vivo, and Antibodies to PspA Are Effective for Therapy in a Murine Model of Pneumococcal Sepsis

Pneumococcal surface protein A (PspA) is an immunogenic protein expressed on the surface of all strains of Streptococcus pneumoniae (pneumococcus) and induces antibodies which protect against invasive infection in mice. Pneumococci used for infectious challenge in protection studies are typically co...

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發表在:	Infect Immun
Principais autores:	Swiatlo, E., King, J., Nabors, G. S., Mathews, B., Briles, D. E.
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 2003
主題:	Microbial Immunity and Vaccines
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC308907/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14638806/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.12.7149-7153.2003
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