Enhanced Immunogenicity of CD4(+) T-Cell Responses and Protective Efficacy of a DNA-Modified Vaccinia Virus Ankara Prime-Boost Vaccination Regimen for Murine Tuberculosis

DNA vaccines whose DNA encodes a variety of antigens from Mycobacterium tuberculosis have been evaluated for immunogenicity and protective efficacy. CD8(+) T-cell responses and protection achieved in other infectious disease models have been optimized by using a DNA immunization to prime the immune...

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Detalhes bibliográficos
Main Authors: McShane, Helen, Brookes, Roger, Gilbert, Sarah C., Hill, Adrian V. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC97939/
https://ncbi.nlm.nih.gov/pubmed/11159955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.2.681-686.2001
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