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Safety and Immunogenicity of DNA Prime and Modified Vaccinia Ankara Virus-HIV Subtype C Vaccine Boost in Healthy Adults

A randomized, double-blind, placebo-controlled phase I trial was conducted in 32 HIV-uninfected healthy volunteers to assess the safety and immunogenicity of 3 doses of DNA vaccine (Advax) plus 1 dose of recombinant modified vaccinia virus Ankara (MVA) (TBC-M4) or 3 doses of TBC-M4 alone (groups A a...

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Bibliografiska uppgifter
Huvudupphovsmän: Hayes, Peter, Gilmour, Jill, von Lieven, Andrea, Gill, Dilbinder, Clark, Lorna, Kopycinski, Jakub, Cheeseman, Hannah, Chung, Amy, Alter, Galit, Dally, Len, Zachariah, Devika, Lombardo, Angela, Ackland, James, Sayeed, Eddy, Jackson, Akil, Boffito, Marta, Gazzard, Brian, Fast, Patricia E., Cox, Josephine H., Laufer, Dagna
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592345/
https://ncbi.nlm.nih.gov/pubmed/23345581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00637-12
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