Safety and Immunogenicity of DNA Prime and Modified Vaccinia Ankara Virus-HIV Subtype C Vaccine Boost in Healthy Adults

A randomized, double-blind, placebo-controlled phase I trial was conducted in 32 HIV-uninfected healthy volunteers to assess the safety and immunogenicity of 3 doses of DNA vaccine (Advax) plus 1 dose of recombinant modified vaccinia virus Ankara (MVA) (TBC-M4) or 3 doses of TBC-M4 alone (groups A a...

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Detalhes bibliográficos
Main Authors: Hayes, Peter, Gilmour, Jill, von Lieven, Andrea, Gill, Dilbinder, Clark, Lorna, Kopycinski, Jakub, Cheeseman, Hannah, Chung, Amy, Alter, Galit, Dally, Len, Zachariah, Devika, Lombardo, Angela, Ackland, James, Sayeed, Eddy, Jackson, Akil, Boffito, Marta, Gazzard, Brian, Fast, Patricia E., Cox, Josephine H., Laufer, Dagna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592345/
https://ncbi.nlm.nih.gov/pubmed/23345581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00637-12
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