Granulocyte-Macrophage Colony-Stimulating Factor-Deficient Mice Have Impaired Resistance to Blood-Stage Malaria

The contribution of granulocyte-macrophage colony-stimulating factor (GM-CSF), a hematopoietic and immunoregulatory cytokine, to resistance to blood-stage malaria was investigated by infecting GM-CSF-deficient (knockout [KO]) mice with Plasmodium chabaudi AS. KO mice were more susceptible to infecti...

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Autors principals: Riopel, Julie, Tam, MiFong, Mohan, Karkada, Marino, Michael W., Stevenson, Mary M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Fungal and Parasitic Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC97864/
https://ncbi.nlm.nih.gov/pubmed/11119498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.1.129-136.2001
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