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The human granulocyte-macrophage colony- stimulating factor gene is autonomously regulated in vivo by an inducible tissue-specific enhancer

The granulocyte-macrophage colony-stimulating factor (GM-CSF) gene is part of a cytokine gene cluster and is directly linked to a conserved upstream inducible enhancer. Here we examined the in vitro and in vivo functions of the human GM-CSF enhancer and found that it was required for the correctly r...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Cockerill, Peter N., Bert, Andrew G., Roberts, Donna, Vadas, Mathew A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24779/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10611344/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.26.15097
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