Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein α-deficient mice

Transcription factors are master regulatory switches of differentiation, including the development of specific hematopoietic lineages from stem cells. Here we show that mice with targeted disruption of the CCAAT enhancer binding protein α gene (C/EBPα) demonstrate a selective block in differentiatio...

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Dong-Er, Zhang, Pu, Wang, Nai-dy, Hetherington, Christopher J., Darlington, Gretchen J., Tenen, Daniel G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences of the USA 1997
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC19554/
https://ncbi.nlm.nih.gov/pubmed/9012825
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