Immunopathologic Effects of Tumor Necrosis Factor Alpha in Murine Mycobacterial Infection Are Dose Dependent

In experimental mycobacterial infection, tumor necrosis factor alpha (TNF-α) is required for control of bacillary growth and the protective granulomatous response, but may cause immunopathology. To directly examine the positive and detrimental effects of this cytokine, a murine model was used in whi...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Bekker, Linda-Gail, Moreira, Andre L., Bergtold, Amy, Freeman, Sherry, Ryffel, Bernard, Kaplan, Gilla
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Bacterial Infections
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97804/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11083819/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.12.6954-6961.2000
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