Identification and Characterization of the scl Gene Encoding a Group A Streptococcus Extracellular Protein Virulence Factor with Similarity to Human Collagen

Group A Streptococcus (GAS) expresses cell surface proteins that mediate important biological functions such as resistance to phagocytosis, adherence to plasma and extracellular matrix proteins, and degradation of host proteins. An open reading frame encoding a protein of 348 amino acid residues was...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Lukomski, Slawomir, Nakashima, Kazumitsu, Abdi, Iman, Cipriano, Vincent J., Ireland, Robin M., Reid, Sean D., Adams, Gerald G., Musser, James M.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97748/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11083763/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.12.6542-6553.2000
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