Extending the CD4(+) T-Cell Epitope Specificity of the Th1 Immune Response to an Antigen Using a Salmonella enterica Serovar Typhimurium Delivery Vehicle

We analyzed the CD4 T-cell immunodominance of the response to a model antigen (Ag), MalE, when delivered by an attenuated strain of Salmonella enterica serovar Typhimurium (SL3261*pMalE). Compared to purified MalE Ag administered with adjuvant, the mapping of the peptide-specific proliferative respo...

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Xehetasun bibliografikoak
Egile Nagusiak: Lo-Man, Richard, Langeveld, Jan P. M., Dériaud, Edith, Jehanno, Muguette, Rojas, Marie, Clément, Jean-Marie, Meloen, Robert H., Hofnung, Maurice, Leclerc, Claude
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2000
Gaiak:
Microbial Immunity and Vaccines
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC97535/
https://ncbi.nlm.nih.gov/pubmed/10816447
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