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Attenuation of and Protection Induced by a Leucine Auxotroph of Mycobacterium tuberculosis

Attenuated mutants of Mycobacterium tuberculosis represent potential vaccine candidates for the prevention of tuberculosis. It is known that auxotrophs of a variety of bacteria are attenuated in vivo and yet provide protection against challenge with wild-type organisms. A leucine auxotroph of M. tub...

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Bibliografski detalji
Glavni autori: Hondalus, Mary K., Bardarov, Stoyan, Russell, Robert, Chan, John, Jacobs, William R., Bloom, Barry R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC97501/
https://ncbi.nlm.nih.gov/pubmed/10768986
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