Characterization of Auxotrophic Mutants of Mycobacterium tuberculosis and Their Potential as Vaccine Candidates

Auxotrophic mutants of Mycobacterium tuberculosis have been proposed as new vaccine candidates. We have analyzed the virulence and vaccine potential of M. tuberculosis strains containing defined mutations in genes involved in methionine (metB), proline (proC), or tryptophan (trpD) amino acid biosynt...

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Bibliographische Detailangaben
Hauptverfasser: Smith, Debbie A., Parish, Tanya, Stoker, Neil G., Bancroft, Gregory J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC97996/
https://ncbi.nlm.nih.gov/pubmed/11160012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.2.1142-1150.2001
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