Inhibition of Vesicular Secretion in Both Neuronal and Nonneuronal Cells by a Retargeted Endopeptidase Derivative of Clostridium botulinum Neurotoxin Type A

Clostridial neurotoxins potently and specifically inhibit neurotransmitter release in defined cell types by a mechanism that involves cleavage of specific components of the vesicle docking/fusion complex, the SNARE complex. A derivative of the type A neurotoxin from Clostridium botulinum (termed LH(...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chaddock, John A., Purkiss, John R., Friis, Lorna M., Broadbridge, Janice D., Duggan, Michael J., Fooks, Sarah J., Shone, Clifford C., Quinn, Conrad P., Foster, Keith A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Molecular and Cellular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC97463/
https://ncbi.nlm.nih.gov/pubmed/10768948
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados