Production of Protective Human Antipneumococcal Antibodies by Transgenic Mice with Human Immunoglobulin Loci

Infections with Streptococcus pneumoniae remain a significant cause of morbidity and mortality. To gain insight into structure-function relationships for human antibodies to pneumococcal capsular polysaccharide (PPS), we studied the response of transgenic mice reconstituted with human immunoglobulin...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Russell, Nina D., Corvalan, Jose R. F., Gallo, Michael L., Davis, C. Geoffrey, Pirofski, Liise-anne
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Microbial Immunity and Vaccines
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97353/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722569/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.4.1820-1826.2000
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