Relative Roles of Pneumolysin and Hydrogen Peroxide from Streptococcus pneumoniae in Inhibition of Ependymal Ciliary Beat Frequency

Ciliated ependymal cells line the ventricular system of the brain and the cerebral aqueducts. This study characterizes the relative roles of pneumolysin and hydrogen peroxide (H(2)O(2)) in pneumococcal meningitis, using the in vitro ependymal ciliary beat frequency (CBF) as an indicator of toxicity....

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Autori principali: Hirst, Robert A., Sikand, Kulvinder S., Rutman, Andrew, Mitchell, Timothy J., Andrew, Peter W., O'Callaghan, Christopher
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
Soggetti:
Molecular and Cellular Pathogenesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC97315/
https://ncbi.nlm.nih.gov/pubmed/10678974
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