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Relative Roles of Pneumolysin and Hydrogen Peroxide from Streptococcus pneumoniae in Inhibition of Ependymal Ciliary Beat Frequency

Ciliated ependymal cells line the ventricular system of the brain and the cerebral aqueducts. This study characterizes the relative roles of pneumolysin and hydrogen peroxide (H(2)O(2)) in pneumococcal meningitis, using the in vitro ependymal ciliary beat frequency (CBF) as an indicator of toxicity....

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Hlavní autoři: Hirst, Robert A., Sikand, Kulvinder S., Rutman, Andrew, Mitchell, Timothy J., Andrew, Peter W., O'Callaghan, Christopher
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC97315/
https://ncbi.nlm.nih.gov/pubmed/10678974
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