Pneumolysin-Dependent and -Independent Gene Expression Identified by cDNA Microarray Analysis of THP-1 Human Mononuclear Cells Stimulated by Streptococcus pneumoniae

Pneumolysin is an important virulence factor of Streptococcus pneumoniae, interacting with the membranes of host cells to elicit a multitude of inflammatory responses. We used cDNA microarrays to identify genes which are responsive to S. pneumoniae in a pneumolysin-dependent and -independent fashion...

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Bibliographic Details
Main Authors: Rogers, P. David, Thornton, Justin, Barker, Katherine S., McDaniel, D. Olga, Sacks, Gordon S., Swiatlo, Edwin, McDaniel, Larry S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC152049/
https://ncbi.nlm.nih.gov/pubmed/12654830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.4.2087-2094.2003
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