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Phase 1 and Phase 2 Studies of Salmonella enterica Serovar Paratyphi A O-Specific Polysaccharide-Tetanus Toxoid Conjugates in Adults, Teenagers, and 2- to 4-Year-Old Children in Vietnam

Salmonella enterica serovar Paratyphi A O-specific polysaccharide (O-SP) was activated with 1-cyano-4-dimethylaminopyridinium tetrafluoroborate (CDAP) and bound to tetanus toxoid (TT) with adipic acid dihydrazide as a linker (SPA-TT(1)) or directly (SPA-TT(2)). In mice, these two conjugates elicited...

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Библиографические подробности
Главные авторы: Konadu, Edward Y., Lin, Feng-Ying C., Hó, Vô Anh, Thuy, Nguyen Thi Thanh, Van Bay, Phan, Thanh, Tran Cong, Khiem, Ha Ba, Trach, Dang Duc, Karpas, Arthur B., Li, Jianping, Bryla, Dolores A., Robbins, John B., Szu, Shousun C.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2000
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC97311/
https://ncbi.nlm.nih.gov/pubmed/10678970
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